BDBM50390907 CHEMBL2071002

SMILES: Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nccs1

InChI Key: InChIKey=AVJXGTCULQJMMN-CQSZACIVSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390907   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
KCNQ (Kv7) potassium channel (Homo sapiens (Human))	BDBM50390907 (CHEMBL2071002) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nccs1 |r| Show InChI InChI=1S/C16H19N3O3S2/c1-12-5-7-13(8-6-12)24(21,22)19-10-3-2-4-14(19)15(20)18-16-17-9-11-23-16/h5-9,11,14H,2-4,10H2,1H3,(H,17,18,20)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activation of Kv7.1 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assay				Bioorg Med Chem Lett 22: 5936-41 (2012) Article DOI: 10.1016/j.bmcl.2012.07.060 BindingDB Entry DOI: 10.7270/Q25T3MKN
					More data for this Ligand-Target Pair