BDBM50390909 CHEMBL2071004

SMILES: Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nc(cs1)-c1ccc2occc2c1

InChI Key: InChIKey=WXMLIBUKUNXGFC-OAQYLSRUSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390909   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
KCNQ (Kv7) potassium channel (Homo sapiens (Human))	BDBM50390909 (CHEMBL2071004) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nc(cs1)-c1ccc2occc2c1 |r| Show InChI InChI=1S/C24H23N3O4S2/c1-16-5-8-19(9-6-16)33(29,30)27-12-3-2-4-21(27)23(28)26-24-25-20(15-32-24)17-7-10-22-18(14-17)11-13-31-22/h5-11,13-15,21H,2-4,12H2,1H3,(H,25,26,28)/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activation of Kv7.1 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assay				Bioorg Med Chem Lett 22: 5936-41 (2012) Article DOI: 10.1016/j.bmcl.2012.07.060 BindingDB Entry DOI: 10.7270/Q25T3MKN
					More data for this Ligand-Target Pair