BDBM50390914 CHEMBL2071009

SMILES: Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nnc(s1)-c1ccc2occc2c1

InChI Key: InChIKey=PNUUEZVTQJSIHD-LJQANCHMSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390914   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
KCNQ (Kv7) potassium channel (Homo sapiens (Human))	BDBM50390914 (CHEMBL2071009) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCCC[C@@H]1C(=O)Nc1nnc(s1)-c1ccc2occc2c1 |r| Show InChI InChI=1S/C23H22N4O4S2/c1-15-5-8-18(9-6-15)33(29,30)27-12-3-2-4-19(27)21(28)24-23-26-25-22(32-23)17-7-10-20-16(14-17)11-13-31-20/h5-11,13-14,19H,2-4,12H2,1H3,(H,24,26,28)/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activation of Kv7.1 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assay				Bioorg Med Chem Lett 22: 5936-41 (2012) Article DOI: 10.1016/j.bmcl.2012.07.060 BindingDB Entry DOI: 10.7270/Q25T3MKN
					More data for this Ligand-Target Pair