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BDBM50390965 CHEMBL2071145

SMILES: CCOC(=O)c1nnn(c1NC(C)=O)-c1ccccc1

InChI Key: InChIKey=WTCNRFUXSFFBGD-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50390965   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 4C


(Homo sapiens (Human))
BDBM50390965
PNG
(CHEMBL2071145)
Show SMILES CCOC(=O)c1nnn(c1NC(C)=O)-c1ccccc1
Show InChI InChI=1S/C13H14N4O3/c1-3-20-13(19)11-12(14-9(2)18)17(16-15-11)10-7-5-4-6-8-10/h4-8H,3H2,1-2H3,(H,14,18)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>2.00E+5n/an/an/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Inhibition of KDM4C catalytic core-mediated demethylation of ARK(Me)3STGGK after 30 mins by FDH-coupled assay


Bioorg Med Chem Lett 22: 5811-3 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.091
BindingDB Entry DOI: 10.7270/Q2222VV7
More data for this
Ligand-Target Pair
Lysine-specific demethylase 4C


(Homo sapiens (Human))
BDBM50390965
PNG
(CHEMBL2071145)
Show SMILES CCOC(=O)c1nnn(c1NC(C)=O)-c1ccccc1
Show InChI InChI=1S/C13H14N4O3/c1-3-20-13(19)11-12(14-9(2)18)17(16-15-11)10-7-5-4-6-8-10/h4-8H,3H2,1-2H3,(H,14,18)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Inhibition of KDM4C catalytic core-mediated demethylation of ARK(Me)3STGGK after 30 mins by FDH-coupled assay


Bioorg Med Chem Lett 22: 5811-3 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.091
BindingDB Entry DOI: 10.7270/Q2222VV7
More data for this
Ligand-Target Pair