BDBM50390969 PYRAZOLE

SMILES: c1cn[nH]c1

InChI Key: InChIKey=WTKZEGDFNFYCGP-UHFFFAOYSA-N

Data: 2 KI  1 IC50  1 Kd

PDB links: 4 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50390969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alcohol dehydrogenase S chain (Equus caballus)	BDBM50390969 (PYRAZOLE) Show SMILES c1cn[nH]c1 Show InChI InChI=1S/C3H4N2/c1-2-4-5-3-1/h1-3H,(H,4,5)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem	PDB PubMed	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against horse liver alcohol dehydrogenase (ADH)				J Med Chem 29: 615-20 (1986) BindingDB Entry DOI: 10.7270/Q22R3TV3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50390969 (PYRAZOLE) Show SMILES c1cn[nH]c1 Show InChI InChI=1S/C3H4N2/c1-2-4-5-3-1/h1-3H,(H,4,5)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem	Article PubMed	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of KDM4C catalytic core-mediated demethylation of ARK(Me)3STGGK after 30 mins by FDH-coupled assay				Bioorg Med Chem Lett 22: 5811-3 (2012) Article DOI: 10.1016/j.bmcl.2012.07.091 BindingDB Entry DOI: 10.7270/Q2222VV7
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50390969 (PYRAZOLE) Show SMILES c1cn[nH]c1 Show InChI InChI=1S/C3H4N2/c1-2-4-5-3-1/h1-3H,(H,4,5)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of KDM4C catalytic core-mediated demethylation of ARK(Me)3STGGK after 30 mins by FDH-coupled assay				Bioorg Med Chem Lett 22: 5811-3 (2012) Article DOI: 10.1016/j.bmcl.2012.07.091 BindingDB Entry DOI: 10.7270/Q2222VV7
					More data for this Ligand-Target Pair
Alcohol dehydrogenase S chain (Equus caballus)	BDBM50390969 (PYRAZOLE) Show SMILES c1cn[nH]c1 Show InChI InChI=1S/C3H4N2/c1-2-4-5-3-1/h1-3H,(H,4,5)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of horse liver alcohol dehydrogenase using ethanol as substrate assessed as dissociation constant by spectrophotometric titration in prese...				J Med Chem 22: 356-9 (1979) Article DOI: 10.1021/jm00190a005 BindingDB Entry DOI: 10.7270/Q26T0QNZ
					More data for this Ligand-Target Pair				3D Structure (crystal)