BDBM50390969 PYRAZOLE
SMILES: c1cn[nH]c1
InChI Key: InChIKey=WTKZEGDFNFYCGP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alcohol dehydrogenase S chain (Equus caballus) | BDBM50390969 (PYRAZOLE) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem | PDB PubMed | 1.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against horse liver alcohol dehydrogenase (ADH) | J Med Chem 29: 615-20 (1986) BindingDB Entry DOI: 10.7270/Q22R3TV3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50390969 (PYRAZOLE) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem | Article PubMed | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of KDM4C catalytic core-mediated demethylation of ARK(Me)3STGGK after 30 mins by FDH-coupled assay | Bioorg Med Chem Lett 22: 5811-3 (2012) Article DOI: 10.1016/j.bmcl.2012.07.091 BindingDB Entry DOI: 10.7270/Q2222VV7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50390969 (PYRAZOLE) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of KDM4C catalytic core-mediated demethylation of ARK(Me)3STGGK after 30 mins by FDH-coupled assay | Bioorg Med Chem Lett 22: 5811-3 (2012) Article DOI: 10.1016/j.bmcl.2012.07.091 BindingDB Entry DOI: 10.7270/Q2222VV7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alcohol dehydrogenase S chain (Equus caballus) | BDBM50390969 (PYRAZOLE) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of horse liver alcohol dehydrogenase using ethanol as substrate assessed as dissociation constant by spectrophotometric titration in prese... | J Med Chem 22: 356-9 (1979) Article DOI: 10.1021/jm00190a005 BindingDB Entry DOI: 10.7270/Q26T0QNZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |