BDBM50391041 CHEMBL2088407

SMILES: Cn1nc(cc1C(=O)Nc1ccc2sc(CO)nc2c1)C(F)(F)F

InChI Key: InChIKey=WGOAUHCYBVWDET-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50391041 (CHEMBL2088407) Show SMILES Cn1nc(cc1C(=O)Nc1ccc2sc(CO)nc2c1)C(F)(F)F Show InChI InChI=1S/C14H11F3N4O2S/c1-21-9(5-11(20-21)14(15,16)17)13(23)18-7-2-3-10-8(4-7)19-12(6-22)24-10/h2-5,22H,6H2,1H3,(H,18,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPV1 receptor assessed as inhibition of capsaicin-induced calcium uptake by FLIPR assay				Bioorg Med Chem Lett 22: 6205-11 (2012) Article DOI: 10.1016/j.bmcl.2012.08.018 BindingDB Entry DOI: 10.7270/Q29C6ZGB
					More data for this Ligand-Target Pair