null

SMILES: [O-][V]([O-])([O-])=O

InChI Key: InChIKey=LSGOVYNHVSXFFJ-UHFFFAOYSA-N

PDB links: 123 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 66 hits for monomerid = 50391109   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein phosphatase S (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hebei University Curated by ChEMBL					Assay Description Inhibition of recombinant human PTPsigma expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed b...				J Nat Prod 82: 2638-2644 (2019) Article DOI: 10.1021/acs.jnatprod.9b00620 BindingDB Entry DOI: 10.7270/Q2KW5KHH
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiao Tong University (SJTU) Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin) using pNPP as substrate after 30 mins				Eur J Med Chem 164: 408-422 (2019) Article DOI: 10.1016/j.ejmech.2018.12.032 BindingDB Entry DOI: 10.7270/Q2KK9G90
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiao Tong University (SJTU) Curated by ChEMBL					Assay Description Inhibition of TCPTP (unknown origin) using pNPP as substrate after 30 mins				Eur J Med Chem 164: 408-422 (2019) Article DOI: 10.1016/j.ejmech.2018.12.032 BindingDB Entry DOI: 10.7270/Q2KK9G90
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens)	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiao Tong University (SJTU) Curated by ChEMBL					Assay Description Inhibition of SHP2 (unknown origin) using pNPP as substrate after 30 mins				Eur J Med Chem 164: 408-422 (2019) Article DOI: 10.1016/j.ejmech.2018.12.032 BindingDB Entry DOI: 10.7270/Q2KK9G90
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens)	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of SHP2 (unknown origin)				Eur J Med Chem 166: 178-185 (2019) Article DOI: 10.1016/j.ejmech.2019.01.057 BindingDB Entry DOI: 10.7270/Q2BR8WM5
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 6 (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of SHP1 (unknown origin)				Eur J Med Chem 166: 178-185 (2019) Article DOI: 10.1016/j.ejmech.2019.01.057 BindingDB Entry DOI: 10.7270/Q2BR8WM5
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of TCPTP (unknown origin)				Eur J Med Chem 166: 178-185 (2019) Article DOI: 10.1016/j.ejmech.2019.01.057 BindingDB Entry DOI: 10.7270/Q2BR8WM5
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-fused PTP1B catalytic domain (1 to 321 residues) (unknown origin) expressed in Escherichia coli using pNPP as substrate measured af...				Eur J Med Chem 166: 178-185 (2019) Article DOI: 10.1016/j.ejmech.2019.01.057 BindingDB Entry DOI: 10.7270/Q2BR8WM5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Receptor-type tyrosine-protein phosphatase F (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of LAR (unknown origin)				Eur J Med Chem 166: 178-185 (2019) Article DOI: 10.1016/j.ejmech.2019.01.057 BindingDB Entry DOI: 10.7270/Q2BR8WM5
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	2.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of PTP1B A27S mutant (unknown origin)				Eur J Med Chem 166: 178-185 (2019) Article DOI: 10.1016/j.ejmech.2019.01.057 BindingDB Entry DOI: 10.7270/Q2BR8WM5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyungpook National University Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...				J Nat Prod 83: 323-332 (2020) Article DOI: 10.1021/acs.jnatprod.9b00777 BindingDB Entry DOI: 10.7270/Q2GM8BVJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hebei Medical University Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...				J Nat Prod 83: 1394-1399 (2020) Article DOI: 10.1021/acs.jnatprod.9b00417 BindingDB Entry DOI: 10.7270/Q2280C67
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens)	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	7.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jiangnan University Curated by ChEMBL					Assay Description Inhibition of SHP2 (unknown origin) using 3-o-methylfluorescein phosphate as substrate by fluorescence assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127170 BindingDB Entry DOI: 10.7270/Q2NP27ZM
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 6 (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jiangnan University Curated by ChEMBL					Assay Description Inhibition of SHP1 (unknown origin) using 3-o-methylfluorescein phosphate as substrate by fluorescence assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127170 BindingDB Entry DOI: 10.7270/Q2NP27ZM
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	2.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jnatprod.2c00879 BindingDB Entry DOI: 10.7270/Q2KW5M40
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jnatprod.2c00879 BindingDB Entry DOI: 10.7270/Q2KW5M40
					More data for this Ligand-Target Pair