null

SMILES: NC(=O)c1ccccc1Oc1ccccc1

InChI Key: InChIKey=CJCOBMTYEDBBSY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50392084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Catenin beta-1 [138-686] (Homo sapiens (Human))	BDBM50392084 (CHEMBL2152586 | US9284299, PNU-74654) Show SMILES NC(=O)c1ccccc1Oc1ccccc1 Show InChI InChI=1S/C13H11NO2/c14-13(15)11-8-4-5-9-12(11)16-10-6-2-1-3-7-10/h1-9H,(H2,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	US Patent	2.44E+4	-6.29	n/a	n/a	n/a	n/a	n/a	7.4	25
University of Utah Research Foundation US Patent					Assay Description Experiments were performed in white opaque 384-well plates from PerkinElmer (Waltham, Mass.), and the samples were read on a Synergy 2 plate reader (...				US Patent US9284299 (2016) BindingDB Entry DOI: 10.7270/Q2WW7GGC
					More data for this Ligand-Target Pair
Catenin beta-1 [138-686] (Homo sapiens (Human))	BDBM50392084 (CHEMBL2152586 | US9284299, PNU-74654) Show SMILES NC(=O)c1ccccc1Oc1ccccc1 Show InChI InChI=1S/C13H11NO2/c14-13(15)11-8-4-5-9-12(11)16-10-6-2-1-3-7-10/h1-9H,(H2,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	US Patent	1.81E+5	-5.10	n/a	n/a	n/a	n/a	n/a	n/a	25
University of Utah Research Foundation US Patent					Assay Description Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino...				US Patent US9284299 (2016) BindingDB Entry DOI: 10.7270/Q2WW7GGC
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50392084 (CHEMBL2152586 | US9284299, PNU-74654) Show SMILES NC(=O)c1ccccc1Oc1ccccc1 Show InChI InChI=1S/C13H11NO2/c14-13(15)11-8-4-5-9-12(11)16-10-6-2-1-3-7-10/h1-9H,(H2,14,15)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...				J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50392084 (CHEMBL2152586 | US9284299, PNU-74654) Show SMILES NC(=O)c1ccccc1Oc1ccccc1 Show InChI InChI=1S/C13H11NO2/c14-13(15)11-8-4-5-9-12(11)16-10-6-2-1-3-7-10/h1-9H,(H2,14,15)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...				J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50392084 (CHEMBL2152586 | US9284299, PNU-74654) Show SMILES NC(=O)c1ccccc1Oc1ccccc1 Show InChI InChI=1S/C13H11NO2/c14-13(15)11-8-4-5-9-12(11)16-10-6-2-1-3-7-10/h1-9H,(H2,14,15)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Guru Jambheshwar University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of SIRT1 (unknown origin) using acetylated lysine as substrate by Fluor de Lys assay				Eur J Med Chem 119: 45-69 (2016) Article DOI: 10.1016/j.ejmech.2016.04.063 BindingDB Entry DOI: 10.7270/Q2VH5QTW
					More data for this Ligand-Target Pair