null

SMILES: NC(=O)c1ccccc1Nc1ccc(NC(=O)c2ccccn2)cc1

InChI Key: InChIKey=PMWXOISVNOISMN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392097   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50392097 (CHEMBL2152599) Show SMILES NC(=O)c1ccccc1Nc1ccc(NC(=O)c2ccccn2)cc1 Show InChI InChI=1S/C19H16N4O2/c20-18(24)15-5-1-2-6-16(15)22-13-8-10-14(11-9-13)23-19(25)17-7-3-4-12-21-17/h1-12,22H,(H2,20,24)(H,23,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...				J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50392097 (CHEMBL2152599) Show SMILES NC(=O)c1ccccc1Nc1ccc(NC(=O)c2ccccn2)cc1 Show InChI InChI=1S/C19H16N4O2/c20-18(24)15-5-1-2-6-16(15)22-13-8-10-14(11-9-13)23-19(25)17-7-3-4-12-21-17/h1-12,22H,(H2,20,24)(H,23,25)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...				J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS
					More data for this Ligand-Target Pair