BDBM50392253 CHEMBL2153495

SMILES: OCCN(CCn1cnc2c1nc[nH]c2=O)CCP(O)(O)=O

InChI Key: InChIKey=WTHKKBBKKSZMJJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50392253   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (Homo sapiens (Human))	BDBM50392253 (CHEMBL2153495) Show SMILES OCCN(CCn1cnc2c1nc[nH]c2=O)CCP(O)(O)=O Show InChI InChI=1S/C11H18N5O5P/c17-5-3-15(4-6-22(19,20)21)1-2-16-8-14-9-10(16)12-7-13-11(9)18/h7-8,17H,1-6H2,(H,12,13,18)(H2,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of human HGPRT using Prib-PP as substrate by spectrophotometric assay in presence of guanine				J Med Chem 55: 6209-23 (2012) Article DOI: 10.1021/jm300662d BindingDB Entry DOI: 10.7270/Q2VX0HND
					More data for this Ligand-Target Pair