BDBM50392264 CHEMBL2153482

SMILES: Nc1nc2n(CCN(CCP(O)(O)=O)CC(O)=O)cnc2c(=O)[nH]1

InChI Key: InChIKey=RPHPTRZESFYTJS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50392264   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (Homo sapiens (Human))	BDBM50392264 (CHEMBL2153482) Show SMILES Nc1nc2n(CCN(CCP(O)(O)=O)CC(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C11H17N6O6P/c12-11-14-9-8(10(20)15-11)13-6-17(9)2-1-16(5-7(18)19)3-4-24(21,22)23/h6H,1-5H2,(H,18,19)(H2,21,22,23)(H3,12,14,15,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of human HGPRT using Prib-PP as substrate by spectrophotometric assay in presence of guanine				J Med Chem 55: 6209-23 (2012) Article DOI: 10.1021/jm300662d BindingDB Entry DOI: 10.7270/Q2VX0HND
					More data for this Ligand-Target Pair