BDBM50392425 CHEMBL2151790
SMILES: CCCCOc1ccc(cc1)C(=O)Nc1ccc(F)cc1F
InChI Key: InChIKey=AHCYOTLTLQTPSU-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor (Rattus norvegicus (Rat)) | BDBM50392425 (CHEMBL2151790) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in human HEK293 cells after 1 hr by scintillation counter | Bioorg Med Chem Lett 22: 6481-5 (2012) Article DOI: 10.1016/j.bmcl.2012.08.043 BindingDB Entry DOI: 10.7270/Q2KD200S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor (Rattus norvegicus (Rat)) | BDBM50392425 (CHEMBL2151790) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 33 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilization | Bioorg Med Chem Lett 22: 6481-5 (2012) Article DOI: 10.1016/j.bmcl.2012.08.043 BindingDB Entry DOI: 10.7270/Q2KD200S | |||||||||||
More data for this Ligand-Target Pair |