BDBM50392504 CHEMBL2152158

SMILES: Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCC(F)(F)C1)c1ccc(Cl)cn1)C(F)(F)F

InChI Key: InChIKey=WOGLBGNRQWGHDT-QBGQUKIHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392504   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50392504 (CHEMBL2152158) Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCC(F)(F)C1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C26H22ClF6N3O/c27-19-6-7-22(34-15-19)25(13-16-4-2-1-3-5-16,17-10-18(26(31,32)33)12-20(28)11-17)36-23(37)35-21-8-9-24(29,30)14-21/h1-7,10-12,15,21H,8-9,13-14H2,(H2,35,36,37)/t21?,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting				Bioorg Med Chem Lett 22: 6503-8 (2012) Article DOI: 10.1016/j.bmcl.2012.08.011 BindingDB Entry DOI: 10.7270/Q2XP761G
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50392504 (CHEMBL2152158) Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCC(F)(F)C1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C26H22ClF6N3O/c27-19-6-7-22(34-15-19)25(13-16-4-2-1-3-5-16,17-10-18(26(31,32)33)12-20(28)11-17)36-23(37)35-21-8-9-24(29,30)14-21/h1-7,10-12,15,21H,8-9,13-14H2,(H2,35,36,37)/t21?,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay				Bioorg Med Chem Lett 22: 6503-8 (2012) Article DOI: 10.1016/j.bmcl.2012.08.011 BindingDB Entry DOI: 10.7270/Q2XP761G
					More data for this Ligand-Target Pair