BDBM50392517 CHEMBL2152170
SMILES: FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CC(F)(F)C1)c1ccc(Cl)cn1
InChI Key: InChIKey=JKPLEZZMLLSVDS-VWLOTQADSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholesteryl ester transfer protein (Homo sapiens (Human)) | BDBM50392517 (CHEMBL2152170) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting | Bioorg Med Chem Lett 22: 6503-8 (2012) Article DOI: 10.1016/j.bmcl.2012.08.011 BindingDB Entry DOI: 10.7270/Q2XP761G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholesteryl ester transfer protein (Homo sapiens (Human)) | BDBM50392517 (CHEMBL2152170) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay | Bioorg Med Chem Lett 22: 6503-8 (2012) Article DOI: 10.1016/j.bmcl.2012.08.011 BindingDB Entry DOI: 10.7270/Q2XP761G | |||||||||||
More data for this Ligand-Target Pair |