BDBM50392528 CHEMBL2152181

SMILES: FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NCC(F)(F)C(F)(F)F)c1ccc(Cl)cn1

InChI Key: InChIKey=MDWIBDBYTJHKEJ-QFIPXVFZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392528   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50392528 (CHEMBL2152181) Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NCC(F)(F)C(F)(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C25H18ClF10N3O2/c26-16-6-7-19(37-12-16)22(11-14-4-2-1-3-5-14,39-21(40)38-13-23(30,31)25(34,35)36)15-8-17(27)10-18(9-15)41-24(32,33)20(28)29/h1-10,12,20H,11,13H2,(H2,38,39,40)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting				Bioorg Med Chem Lett 22: 6503-8 (2012) Article DOI: 10.1016/j.bmcl.2012.08.011 BindingDB Entry DOI: 10.7270/Q2XP761G
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50392528 (CHEMBL2152181) Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NCC(F)(F)C(F)(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C25H18ClF10N3O2/c26-16-6-7-19(37-12-16)22(11-14-4-2-1-3-5-14,39-21(40)38-13-23(30,31)25(34,35)36)15-8-17(27)10-18(9-15)41-24(32,33)20(28)29/h1-10,12,20H,11,13H2,(H2,38,39,40)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay				Bioorg Med Chem Lett 22: 6503-8 (2012) Article DOI: 10.1016/j.bmcl.2012.08.011 BindingDB Entry DOI: 10.7270/Q2XP761G
					More data for this Ligand-Target Pair