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BDBM50392711 CHEMBL2151380

SMILES: Cc1ccc(CC2CN(N=C2c2ccc(Cl)c(C)c2)C(=O)NC2C(C)(C)C3CCC2(C)C3)cc1

InChI Key: InChIKey=SAZCFFCYWUHWFV-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50392711   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50392711
PNG
(CHEMBL2151380)
Show SMILES Cc1ccc(CC2CN(N=C2c2ccc(Cl)c(C)c2)C(=O)NC2C(C)(C)C3CCC2(C)C3)cc1 |c:9|
Show InChI InChI=1S/C29H36ClN3O/c1-18-6-8-20(9-7-18)15-22-17-33(32-25(22)21-10-11-24(30)19(2)14-21)27(34)31-26-28(3,4)23-12-13-29(26,5)16-23/h6-11,14,22-23,26H,12-13,15-17H2,1-5H3,(H,31,34)
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PC cid
PC sid
UniChem
Article
PubMed
251n/an/an/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes after 1 hr by scintillation counting


Eur J Med Chem 58: 396-404 (2012)


Article DOI: 10.1016/j.ejmech.2012.10.031
BindingDB Entry DOI: 10.7270/Q2474BZG
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50392711
PNG
(CHEMBL2151380)
Show SMILES Cc1ccc(CC2CN(N=C2c2ccc(Cl)c(C)c2)C(=O)NC2C(C)(C)C3CCC2(C)C3)cc1 |c:9|
Show InChI InChI=1S/C29H36ClN3O/c1-18-6-8-20(9-7-18)15-22-17-33(32-25(22)21-10-11-24(30)19(2)14-21)27(34)31-26-28(3,4)23-12-13-29(26,5)16-23/h6-11,14,22-23,26H,12-13,15-17H2,1-5H3,(H,31,34)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Avenue de l'Universit£

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cell membranes after 1 hr by scintillation counting


Eur J Med Chem 58: 396-404 (2012)


Article DOI: 10.1016/j.ejmech.2012.10.031
BindingDB Entry DOI: 10.7270/Q2474BZG
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50392711
PNG
(CHEMBL2151380)
Show SMILES Cc1ccc(CC2CN(N=C2c2ccc(Cl)c(C)c2)C(=O)NC2C(C)(C)C3CCC2(C)C3)cc1 |c:9|
Show InChI InChI=1S/C29H36ClN3O/c1-18-6-8-20(9-7-18)15-22-17-33(32-25(22)21-10-11-24(30)19(2)14-21)27(34)31-26-28(3,4)23-12-13-29(26,5)16-23/h6-11,14,22-23,26H,12-13,15-17H2,1-5H3,(H,31,34)
PDB

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antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 191n/an/an/an/a



Avenue de l'Universit£

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assay


Eur J Med Chem 58: 396-404 (2012)


Article DOI: 10.1016/j.ejmech.2012.10.031
BindingDB Entry DOI: 10.7270/Q2474BZG
More data for this
Ligand-Target Pair