BDBM50392790 CHEMBL2151320::US8486966, 16
SMILES: C[C@H](Nc1ccc2ncn(-c3cc(C)[nH]n3)c2n1)c1ncc(F)cn1
InChI Key: InChIKey=SKSNCQVCTOVJTO-JTQLQIEISA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50392790 (CHEMBL2151320 | US8486966, 16) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of human ERG | ACS Med Chem Lett 3: 705-709 (2012) Article DOI: 10.1021/ml300074j BindingDB Entry DOI: 10.7270/Q2GH9K2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM50392790 (CHEMBL2151320 | US8486966, 16) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | 25 |
Astrazeneca AB US Patent | Assay Description JAK2 and Trk A kinase activity was determined by measuring the kinase's ability to phoshorylate synthetic tyrosine residues within a generic poly... | US Patent US8486966 (2013) BindingDB Entry DOI: 10.7270/Q26T0K7X | |||||||||||
More data for this Ligand-Target Pair |