BDBM50392852 CHEMBL2151193

SMILES: COc1ccc(cc1)-c1nnc2sc3c(ccc4ccccc34)n12

InChI Key: InChIKey=HLIMLOCFQJDVDJ-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50392852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392852 (CHEMBL2151193) Show SMILES COc1ccc(cc1)-c1nnc2sc3c(ccc4ccccc34)n12 Show InChI InChI=1S/C19H13N3OS/c1-23-14-9-6-13(7-10-14)18-20-21-19-22(18)16-11-8-12-4-2-3-5-15(12)17(16)24-19/h2-11H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of p38MAPKalpha using GST-ATF2 (1 to 115) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 mins by ...				ACS Med Chem Lett 3: 721-725 (2012) Article DOI: 10.1021/ml300129b BindingDB Entry DOI: 10.7270/Q2ZG6T9C
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50392852 (CHEMBL2151193) Show SMILES COc1ccc(cc1)-c1nnc2sc3c(ccc4ccccc34)n12 Show InChI InChI=1S/C19H13N3OS/c1-23-14-9-6-13(7-10-14)18-20-21-19-22(18)16-11-8-12-4-2-3-5-15(12)17(16)24-19/h2-11H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of FITC-JIP peptide from human His-tagged JNK2alpha2 after 30 mins by fluorescence assay				ACS Med Chem Lett 3: 721-725 (2012) Article DOI: 10.1021/ml300129b BindingDB Entry DOI: 10.7270/Q2ZG6T9C
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50392852 (CHEMBL2151193) Show SMILES COc1ccc(cc1)-c1nnc2sc3c(ccc4ccccc34)n12 Show InChI InChI=1S/C19H13N3OS/c1-23-14-9-6-13(7-10-14)18-20-21-19-22(18)16-11-8-12-4-2-3-5-15(12)17(16)24-19/h2-11H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human JNK2alpha2 using GST-c-jun (1 to 221) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 min...				ACS Med Chem Lett 3: 721-725 (2012) Article DOI: 10.1021/ml300129b BindingDB Entry DOI: 10.7270/Q2ZG6T9C
					More data for this Ligand-Target Pair
ERK-2 (Rattus norvegicus (rat))	BDBM50392852 (CHEMBL2151193) Show SMILES COc1ccc(cc1)-c1nnc2sc3c(ccc4ccccc34)n12 Show InChI InChI=1S/C19H13N3OS/c1-23-14-9-6-13(7-10-14)18-20-21-19-22(18)16-11-8-12-4-2-3-5-15(12)17(16)24-19/h2-11H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat ERK2 using Ets1 (1 to 138) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 mins by liquid s...				ACS Med Chem Lett 3: 721-725 (2012) Article DOI: 10.1021/ml300129b BindingDB Entry DOI: 10.7270/Q2ZG6T9C
					More data for this Ligand-Target Pair