BDBM50393083 CHEMBL2152859

SMILES: Clc1ccc2[nH]cc(CCNC(=O)c3ccccc3-c3ccc(cc3)C#N)c2c1

InChI Key: InChIKey=FCSWXUCDKVWJEN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50393083   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tau (Homo sapiens (Human))	BDBM50393083 (CHEMBL2152859) Show SMILES Clc1ccc2[nH]cc(CCNC(=O)c3ccccc3-c3ccc(cc3)C#N)c2c1 Show InChI InChI=1S/C24H18ClN3O/c25-19-9-10-23-22(13-19)18(15-28-23)11-12-27-24(29)21-4-2-1-3-20(21)17-7-5-16(14-26)6-8-17/h1-10,13,15,28H,11-12H2,(H,27,29)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	325	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Tau phosphorylation by cell based assay				ACS Med Chem Lett 3: 788-788 (2012) Article DOI: 10.1021/ml3002488 BindingDB Entry DOI: 10.7270/Q2H9968V
					More data for this Ligand-Target Pair