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SMILES: Nc1nc2c(nccc2[nH]1)-c1ccco1

InChI Key: InChIKey=MJNLEGDDXDONRO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50393110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50393110 (CHEMBL2153260) Show SMILES Nc1nc2c(nccc2[nH]1)-c1ccco1 Show InChI InChI=1S/C10H8N4O/c11-10-13-6-3-4-12-9(8(6)14-10)7-2-1-5-15-7/h1-5H,(H3,11,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Macquarie University Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by...				J Med Chem 54: 2492-503 (2011) Article DOI: 10.1021/jm200039m BindingDB Entry DOI: 10.7270/Q2QV3NMT
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50393110 (CHEMBL2153260) Show SMILES Nc1nc2c(nccc2[nH]1)-c1ccco1 Show InChI InChI=1S/C10H8N4O/c11-10-13-6-3-4-12-9(8(6)14-10)7-2-1-5-15-7/h1-5H,(H3,11,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Macquarie University Curated by ChEMBL					Assay Description Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...				J Med Chem 54: 2492-503 (2011) Article DOI: 10.1021/jm200039m BindingDB Entry DOI: 10.7270/Q2QV3NMT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50393110 (CHEMBL2153260) Show SMILES Nc1nc2c(nccc2[nH]1)-c1ccco1 Show InChI InChI=1S/C10H8N4O/c11-10-13-6-3-4-12-9(8(6)14-10)7-2-1-5-15-7/h1-5H,(H3,11,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Macquarie University Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using [gamma-32P] ATP after 30 mins by scintillation counting				J Med Chem 54: 2492-503 (2011) Article DOI: 10.1021/jm200039m BindingDB Entry DOI: 10.7270/Q2QV3NMT
					More data for this Ligand-Target Pair