BDBM50393114 CHEMBL2153267
SMILES: Nc1nc2c(nccc2[nH]1)-c1ccccc1
InChI Key: InChIKey=FPXFUSUCOYNPNT-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human)) | BDBM50393114 (CHEMBL2153267) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Macquarie University Curated by ChEMBL | Assay Description Inhibition of human recombinant CDK5/p25 using [gamma-32P] ATP after 30 mins by scintillation counting | J Med Chem 54: 2492-503 (2011) Article DOI: 10.1021/jm200039m BindingDB Entry DOI: 10.7270/Q2QV3NMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT) | BDBM50393114 (CHEMBL2153267) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Macquarie University Curated by ChEMBL | Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation counting | J Med Chem 54: 2492-503 (2011) Article DOI: 10.1021/jm200039m BindingDB Entry DOI: 10.7270/Q2QV3NMT | |||||||||||
More data for this Ligand-Target Pair |