BDBM50393118 CHEMBL2153441

SMILES: Fc1ccc(cc1C(F)(F)F)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)cc1

InChI Key: InChIKey=MXPXPORFELTQAO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50393118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393118 (CHEMBL2153441) Show SMILES Fc1ccc(cc1C(F)(F)F)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)cc1 Show InChI InChI=1S/C26H21F4N3O/c27-23-13-11-20(15-22(23)26(28,29)30)18-8-6-17(7-9-18)16-32-24(34)5-1-4-21-12-10-19-3-2-14-31-25(19)33-21/h2-3,6-15H,1,4-5,16H2,(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair