BDBM50393125 CHEMBL2153448

SMILES: FC(F)(F)Oc1cccc(c1)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)cc1

InChI Key: InChIKey=IYJBGUHBYDUPEB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50393125   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393125 (CHEMBL2153448) Show SMILES FC(F)(F)Oc1cccc(c1)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)cc1 Show InChI InChI=1S/C26H22F3N3O2/c27-26(28,29)34-23-7-1-4-21(16-23)19-11-9-18(10-12-19)17-31-24(33)8-2-6-22-14-13-20-5-3-15-30-25(20)32-22/h1,3-5,7,9-16H,2,6,8,17H2,(H,31,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair