BDBM50393126 CHEMBL2153457

SMILES: Cc1cc(ccc1Cl)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)cc1

InChI Key: InChIKey=OPMDDTWHVKMKPQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50393126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393126 (CHEMBL2153457) Show SMILES Cc1cc(ccc1Cl)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)cc1 Show InChI InChI=1S/C26H24ClN3O/c1-18-16-22(12-14-24(18)27)20-9-7-19(8-10-20)17-29-25(31)6-2-5-23-13-11-21-4-3-15-28-26(21)30-23/h3-4,7-16H,2,5-6,17H2,1H3,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair