BDBM50393131 CHEMBL2153463

SMILES: OC(C(=O)NCc1ccc(cc1)-c1ccc(F)c(c1)C(F)(F)F)(c1ccc(cc1)-c1ccc2cccnc2n1)C(F)(F)F

InChI Key: InChIKey=IFYAGVZPYUZBML-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50393131   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393131 (CHEMBL2153463) Show SMILES OC(C(=O)NCc1ccc(cc1)-c1ccc(F)c(c1)C(F)(F)F)(c1ccc(cc1)-c1ccc2cccnc2n1)C(F)(F)F Show InChI InChI=1S/C31H20F7N3O2/c32-25-13-9-22(16-24(25)30(33,34)35)19-5-3-18(4-6-19)17-40-28(42)29(43,31(36,37)38)23-11-7-20(8-12-23)26-14-10-21-2-1-15-39-27(21)41-26/h1-16,43H,17H2,(H,40,42)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair