BDBM50393138 CHEMBL2153470

SMILES: Fc1ccc(cc1C(F)(F)F)-c1cnc(CNC(=O)CCCc2ccc3cccnc3n2)nc1

InChI Key: InChIKey=PDSXXHYTOAMMPD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50393138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393138 (CHEMBL2153470) Show SMILES Fc1ccc(cc1C(F)(F)F)-c1cnc(CNC(=O)CCCc2ccc3cccnc3n2)nc1 Show InChI InChI=1S/C24H19F4N5O/c25-20-9-7-16(11-19(20)24(26,27)28)17-12-30-21(31-13-17)14-32-22(34)5-1-4-18-8-6-15-3-2-10-29-23(15)33-18/h2-3,6-13H,1,4-5,14H2,(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair