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SMILES: Fc1ccc(cc1C(F)(F)F)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)nn1

InChI Key: InChIKey=JZMUHLQNGXIGBL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50393139   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Succinate receptor 1


(Homo sapiens (Human))		BDBM50393139
PNG
(CHEMBL2153471)
Show SMILES Fc1ccc(cc1C(F)(F)F)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)nn1
Show InChI InChI=1S/C24H19F4N5O/c25-20-10-7-16(13-19(20)24(26,27)28)21-11-9-18(32-33-21)14-30-22(34)5-1-4-17-8-6-15-3-2-12-29-23(15)31-17/h2-3,6-13H,1,4-5,14H2,(H,30,34)
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n/an/a 720n/an/an/an/an/an/a



Advinus Therapeutics

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...

Bioorg Med Chem Lett 21: 3596-602 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.091
BindingDB Entry DOI: 10.7270/Q2BK1DG6
More data for this
Ligand-Target Pair