BDBM50393447 CHEMBL2159506

SMILES: CC(=O)c1cc(C#N)c(Sc2ccc(Cl)cc2Cl)s1

InChI Key: InChIKey=RQXYWMTUIQUROJ-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50393447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 47 (Homo sapiens (Human))	BDBM50393447 (CHEMBL2159506) Show SMILES CC(=O)c1cc(C#N)c(Sc2ccc(Cl)cc2Cl)s1 Show InChI InChI=1S/C13H7Cl2NOS2/c1-7(17)12-4-8(6-16)13(19-12)18-11-3-2-9(14)5-10(11)15/h2-5H,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.16E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of USP47 by Ub-CHOP reporter assay				ACS Med Chem Lett 3: 789-792 (2012) Article DOI: 10.1021/ml200276j BindingDB Entry DOI: 10.7270/Q2154J51
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50393447 (CHEMBL2159506) Show SMILES CC(=O)c1cc(C#N)c(Sc2ccc(Cl)cc2Cl)s1 Show InChI InChI=1S/C13H7Cl2NOS2/c1-7(17)12-4-8(6-16)13(19-12)18-11-3-2-9(14)5-10(11)15/h2-5H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assay				ACS Med Chem Lett 3: 789-792 (2012) Article DOI: 10.1021/ml200276j BindingDB Entry DOI: 10.7270/Q2154J51
					More data for this Ligand-Target Pair