BDBM50393448 CHEMBL2159507
SMILES: CN(C)CCCOc1ccc(NC(=O)c2cc(C#N)c(Sc3c(Cl)cncc3Cl)s2)cc1
InChI Key: InChIKey=GWIKNAKBVWBXMY-UHFFFAOYSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ubiquitin carboxyl-terminal hydrolase 47 (Homo sapiens (Human)) | BDBM50393448 (CHEMBL2159507) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 350 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of USP47 by Ub-CHOP reporter assay | ACS Med Chem Lett 3: 789-792 (2012) Article DOI: 10.1021/ml200276j BindingDB Entry DOI: 10.7270/Q2154J51 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human)) | BDBM50393448 (CHEMBL2159507) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 380 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assay | ACS Med Chem Lett 3: 789-792 (2012) Article DOI: 10.1021/ml200276j BindingDB Entry DOI: 10.7270/Q2154J51 | |||||||||||
More data for this Ligand-Target Pair |