null

SMILES: CCOc1ccc(NC(=O)CSc2nc3c(C)cc(C)cc3cc2C#N)cc1

InChI Key: InChIKey=ORIMLLOCUNVKHP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50393491   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50393491 (CHEMBL2159932) Show SMILES CCOc1ccc(NC(=O)CSc2nc3c(C)cc(C)cc3cc2C#N)cc1 Show InChI InChI=1S/C22H21N3O2S/c1-4-27-19-7-5-18(6-8-19)24-20(26)13-28-22-17(12-23)11-16-10-14(2)9-15(3)21(16)25-22/h5-11H,4,13H2,1-3H3,(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of LMPTP-A expressed in Escherichia coli BL21 using pNPP substrate				J Med Chem 54: 1640-54 (2011) Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human))	BDBM50393491 (CHEMBL2159932) Show SMILES CCOc1ccc(NC(=O)CSc2nc3c(C)cc(C)cc3cc2C#N)cc1 Show InChI InChI=1S/C22H21N3O2S/c1-4-27-19-7-5-18(6-8-19)24-20(26)13-28-22-17(12-23)11-16-10-14(2)9-15(3)21(16)25-22/h5-11H,4,13H2,1-3H3,(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of LYP expressed in Escherichia coli BL21 using pNPP substrate				J Med Chem 54: 1640-54 (2011) Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 7 (Homo sapiens (Human))	BDBM50393491 (CHEMBL2159932) Show SMILES CCOc1ccc(NC(=O)CSc2nc3c(C)cc(C)cc3cc2C#N)cc1 Show InChI InChI=1S/C22H21N3O2S/c1-4-27-19-7-5-18(6-8-19)24-20(26)13-28-22-17(12-23)11-16-10-14(2)9-15(3)21(16)25-22/h5-11H,4,13H2,1-3H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of HePTP expressed in Escherichia coli BL21 using pNPP substrate				J Med Chem 54: 1640-54 (2011) Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 12 (Homo sapiens (Human))	BDBM50393491 (CHEMBL2159932) Show SMILES CCOc1ccc(NC(=O)CSc2nc3c(C)cc(C)cc3cc2C#N)cc1 Show InChI InChI=1S/C22H21N3O2S/c1-4-27-19-7-5-18(6-8-19)24-20(26)13-28-22-17(12-23)11-16-10-14(2)9-15(3)21(16)25-22/h5-11H,4,13H2,1-3H3,(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of PTP-PEST expressed in Escherichia coli BL21 using pNPP substrate				J Med Chem 54: 1640-54 (2011) Article DOI: 10.1021/jm101202j BindingDB Entry DOI: 10.7270/Q2RN38Z0
					More data for this Ligand-Target Pair