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SMILES: CN(C)CCOc1ccc(cc1)C(=O)\C=C\c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=OFCIHDDKDVHWGO-LICLKQGHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50393707   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Quinolone resistance protein NorA


(Staphylococcus aureus)		BDBM50393707
PNG
(CHEMBL2158998)
Show SMILES CN(C)CCOc1ccc(cc1)C(=O)\C=C\c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C25H25NO3/c1-26(2)18-19-28-22-15-11-21(12-16-22)25(27)17-10-20-8-13-24(14-9-20)29-23-6-4-3-5-7-23/h3-17H,18-19H2,1-2H3/b17-10+
PDB

KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Inhibition of norA-mediated ethidium bromide efflux in methicillin-resistant Staphylococcus aureus SA-1199B by spectrofluorometric analysis

Bioorg Med Chem 20: 4514-21 (2012)


Article DOI: 10.1016/j.bmc.2012.05.025
BindingDB Entry DOI: 10.7270/Q2K075D0
More data for this
Ligand-Target Pair