BDBM50393820 CHEMBL2159567

SMILES: FC(F)(F)c1cc(ccc1C1=NOC2CCCCC12)C#N

InChI Key: InChIKey=ZPKULMGMEASWIO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50393820   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50393820 (CHEMBL2159567) Show SMILES FC(F)(F)c1cc(ccc1C1=NOC2CCCCC12)C#N |t:11| Show InChI InChI=1S/C15H13F3N2O/c16-15(17,18)12-7-9(8-19)5-6-10(12)14-11-3-1-2-4-13(11)21-20-14/h5-7,11,13H,1-4H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Eastern Finland Curated by ChEMBL					Assay Description Displacement of [3H]R1881 from wild type human androgen receptor expressed in COS-1 cells co-transfected with pSG5 after 15 mins by scintillation ass...				J Med Chem 55: 6316-27 (2012) Article DOI: 10.1021/jm300233k BindingDB Entry DOI: 10.7270/Q2NS0W1N
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50393820 (CHEMBL2159567) Show SMILES FC(F)(F)c1cc(ccc1C1=NOC2CCCCC12)C#N |t:11| Show InChI InChI=1S/C15H13F3N2O/c16-15(17,18)12-7-9(8-19)5-6-10(12)14-11-3-1-2-4-13(11)21-20-14/h5-7,11,13H,1-4H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Eastern Finland Curated by ChEMBL					Assay Description Displacement of [3H]R1881 from wild type human androgen receptor expressed in COS-1 cells co-transfected with pSG5 after 15 mins by scintillation ass...				J Med Chem 55: 6316-27 (2012) Article DOI: 10.1021/jm300233k BindingDB Entry DOI: 10.7270/Q2NS0W1N
					More data for this Ligand-Target Pair