BDBM50393828 CHEMBL2159730

SMILES: FC(F)(F)c1cc(ccc1C#N)C1=NO[C@@H]2CCC[C@H]12

InChI Key: InChIKey=BRDCBMNKBRNPRG-CMPLNLGQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50393828   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50393828 (CHEMBL2159730) Show SMILES FC(F)(F)c1cc(ccc1C#N)C1=NO[C@@H]2CCC[C@H]12 |r,t:13| Show InChI InChI=1S/C14H11F3N2O/c15-14(16,17)11-6-8(4-5-9(11)7-18)13-10-2-1-3-12(10)20-19-13/h4-6,10,12H,1-3H2/t10-,12+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	224	n/a	n/a	n/a	n/a	n/a	n/a
University of Eastern Finland Curated by ChEMBL					Assay Description Displacement of [3H]R1881 from wild type human androgen receptor expressed in COS-1 cells co-transfected with pSG5 after 15 mins by scintillation ass...				J Med Chem 55: 6316-27 (2012) Article DOI: 10.1021/jm300233k BindingDB Entry DOI: 10.7270/Q2NS0W1N
					More data for this Ligand-Target Pair