null

SMILES: COc1cc(Cl)c(cc1O)-c1nc(SCC(=O)N(C)C)nc2[nH]cc(C#N)c12

InChI Key: InChIKey=CNCOWHMBYWEBGS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50394054 (CHEMBL2158561) Show SMILES COc1cc(Cl)c(cc1O)-c1nc(SCC(=O)N(C)C)nc2[nH]cc(C#N)c12 Show InChI InChI=1S/C18H16ClN5O3S/c1-24(2)14(26)8-28-18-22-16(15-9(6-20)7-21-17(15)23-18)10-4-12(25)13(27-3)5-11(10)19/h4-5,7,25H,8H2,1-3H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]-dofetilide from human ERG				Bioorg Med Chem 20: 6770-89 (2012) Article DOI: 10.1016/j.bmc.2012.08.050 BindingDB Entry DOI: 10.7270/Q2KS6SN4
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50394054 (CHEMBL2158561) Show SMILES COc1cc(Cl)c(cc1O)-c1nc(SCC(=O)N(C)C)nc2[nH]cc(C#N)c12 Show InChI InChI=1S/C18H16ClN5O3S/c1-24(2)14(26)8-28-18-22-16(15-9(6-20)7-21-17(15)23-18)10-4-12(25)13(27-3)5-11(10)19/h4-5,7,25H,8H2,1-3H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis Ltd. Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in HEK293 cells by voltage-clamp method				Bioorg Med Chem 20: 6770-89 (2012) Article DOI: 10.1016/j.bmc.2012.08.050 BindingDB Entry DOI: 10.7270/Q2KS6SN4
					More data for this Ligand-Target Pair