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BDBM50394410 CHEMBL2158156

SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)C(=O)c1occ2c1[C@]3(C)CCC2=O

InChI Key: InChIKey=CDGIQLQWGYQLIH-CLQZEHDMSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50394410   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
p110α/p85α


(Homo sapiens (Human))
BDBM50394410
PNG
(CHEMBL2158156)
Show SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)C(=O)c1occ2c1[C@]3(C)CCC2=O |r|
Show InChI InChI=1S/C20H22O4/c1-19-7-5-12-15(11(19)3-4-14(19)22)17(23)18-16-10(9-24-18)13(21)6-8-20(12,16)2/h9,11-12,15H,3-8H2,1-2H3/t11-,12-,15-,19-,20+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 339n/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Inhibition of human recombinant P110alpha/p85alpha using phosphatidyl inositol as substrate after 1 hr by ADP-Glo Kinase assay


Bioorg Med Chem Lett 22: 6919-22 (2012)


Article DOI: 10.1016/j.bmcl.2012.09.015
BindingDB Entry DOI: 10.7270/Q2MK6F0Q
More data for this
Ligand-Target Pair