BDBM50394410 CHEMBL2158156
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)C(=O)c1occ2c1[C@]3(C)CCC2=O
InChI Key: InChIKey=CDGIQLQWGYQLIH-CLQZEHDMSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p110α/p85α (Homo sapiens (Human)) | BDBM50394410 (CHEMBL2158156) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 339 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut Curated by ChEMBL | Assay Description Inhibition of human recombinant P110alpha/p85alpha using phosphatidyl inositol as substrate after 1 hr by ADP-Glo Kinase assay | Bioorg Med Chem Lett 22: 6919-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.015 BindingDB Entry DOI: 10.7270/Q2MK6F0Q | |||||||||||
More data for this Ligand-Target Pair |