BDBM50394687 CHEMBL2165627

SMILES: OC(=O)C(=O)Nc1ccc(NC(=O)[C@H](CC2CCCC2)n2cnc(c2)C(F)(F)F)nc1

InChI Key: InChIKey=UIPQUPAUXQPGNS-ZDUSSCGKSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50394687   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50394687 (CHEMBL2165627) Show SMILES OC(=O)C(=O)Nc1ccc(NC(=O)[C@H](CC2CCCC2)n2cnc(c2)C(F)(F)F)nc1 |r| Show InChI InChI=1S/C19H20F3N5O4/c20-19(21,22)14-9-27(10-24-14)13(7-11-3-1-2-4-11)16(28)26-15-6-5-12(8-23-15)25-17(29)18(30)31/h5-6,8-11,13H,1-4,7H2,(H,25,29)(H,30,31)(H,23,26,28)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	456	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometric analysis				J Med Chem 55: 1318-33 (2012) Article DOI: 10.1021/jm2014887 BindingDB Entry DOI: 10.7270/Q2NG4RRT
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