BDBM50394688 CHEMBL2165626

SMILES: FC(F)(F)c1cn(cn1)[C@@H](CC1CCCC1)C(=O)Nc1ccc(cn1)-c1nnn[nH]1

InChI Key: InChIKey=NZPVBFBSYBVMPK-ZDUSSCGKSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50394688   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50394688 (CHEMBL2165626) Show SMILES FC(F)(F)c1cn(cn1)[C@@H](CC1CCCC1)C(=O)Nc1ccc(cn1)-c1nnn[nH]1 |r| Show InChI InChI=1S/C18H19F3N8O/c19-18(20,21)14-9-29(10-23-14)13(7-11-3-1-2-4-11)17(30)24-15-6-5-12(8-22-15)16-25-27-28-26-16/h5-6,8-11,13H,1-4,7H2,(H,22,24,30)(H,25,26,27,28)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	284	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometric analysis				J Med Chem 55: 1318-33 (2012) Article DOI: 10.1021/jm2014887 BindingDB Entry DOI: 10.7270/Q2NG4RRT
					More data for this Ligand-Target Pair