BDBM50394989 CHEMBL2163460::US9708370, 62 CP-AP-4

SMILES: NCCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCCN1C(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(N)=O

InChI Key: InChIKey=ULVDYNKBMSCUJK-CSDNOSTESA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50394989   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50394989 (CHEMBL2163460 | US9708370, 62 CP-AP-4) Show SMILES NCCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCCN1C(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(N)=O |r| Show InChI InChI=1S/C47H57N13O6/c48-18-9-8-17-38(42(50)61)55-44(63)39(21-29-11-2-1-3-12-29)56-45(64)40(22-30-25-52-36-15-6-4-13-33(30)36)58-47(66)60-20-10-19-59(60)46(65)41(23-31-26-53-37-16-7-5-14-34(31)37)57-43(62)35(49)24-32-27-51-28-54-32/h1-7,11-16,25-28,35,38-41,52-53H,8-10,17-24,48-49H2,(H2,50,61)(H,51,54)(H,55,63)(H,56,64)(H,57,62)(H,58,66)/t35-,38-,39+,40-,41+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]ghrelin expressed in in LLC-PK1 cells incubated for 1 hr by gamma counting method				J Med Chem 55: 6502-11 (2012) Article DOI: 10.1021/jm300557t BindingDB Entry DOI: 10.7270/Q22J6D00
					More data for this Ligand-Target Pair
Ghrelin receptor (Homo sapiens (Human))	BDBM50394989 (CHEMBL2163460 | US9708370, 62 CP-AP-4) Show SMILES NCCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCCN1C(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(N)=O |r| Show InChI InChI=1S/C47H57N13O6/c48-18-9-8-17-38(42(50)61)55-44(63)39(21-29-11-2-1-3-12-29)56-45(64)40(22-30-25-52-36-15-6-4-13-33(30)36)58-47(66)60-20-10-19-59(60)46(65)41(23-31-26-53-37-16-7-5-14-34(31)37)57-43(62)35(49)24-32-27-51-28-54-32/h1-7,11-16,25-28,35,38-41,52-53H,8-10,17-24,48-49H2,(H2,50,61)(H,51,54)(H,55,63)(H,56,64)(H,57,62)(H,58,66)/t35-,38-,39+,40-,41+/m0/s1	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
VALORISATION-RECHERCHE, LIMITED PARTNERSHIP; VALORISATION HSJ, LIMITED PARTNERSHIP US Patent					Assay Description GHS-R1a radioreceptor assay using LLCPK-1 membranes overexpressing GSH-R1a and radioiodinated (1-28) rat ghrelin as tracer.				US Patent US9708370 (2017) BindingDB Entry DOI: 10.7270/Q2XP76ZK
					More data for this Ligand-Target Pair
Platelet glycoprotein 4 (Rattus norvegicus)	BDBM50394989 (CHEMBL2163460 | US9708370, 62 CP-AP-4) Show SMILES NCCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCCN1C(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(N)=O |r| Show InChI InChI=1S/C47H57N13O6/c48-18-9-8-17-38(42(50)61)55-44(63)39(21-29-11-2-1-3-12-29)56-45(64)40(22-30-25-52-36-15-6-4-13-33(30)36)58-47(66)60-20-10-19-59(60)46(65)41(23-31-26-53-37-16-7-5-14-34(31)37)57-43(62)35(49)24-32-27-51-28-54-32/h1-7,11-16,25-28,35,38-41,52-53H,8-10,17-24,48-49H2,(H2,50,61)(H,51,54)(H,55,63)(H,56,64)(H,57,62)(H,58,66)/t35-,38-,39+,40-,41+/m0/s1	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Displacement of photoactivatable [125I]-Tyr-Bpa-Ala-Hexarelin from CD36 in Sprague-Dawley rat cardiac membranes incubated for 60 mins by densitometry				J Med Chem 55: 6502-11 (2012) Article DOI: 10.1021/jm300557t BindingDB Entry DOI: 10.7270/Q22J6D00
					More data for this Ligand-Target Pair