BDBM50394993 CHEMBL2163485::US9708370, CP-1A(iv)

SMILES: C[C@H](N)C(=O)NN(Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key: InChIKey=QHXNOHMVHGSCFK-ZXPXEFADSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50394993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet glycoprotein 4 (Rattus norvegicus)	BDBM50394993 (CHEMBL2163485 | US9708370, CP-1A(iv)) Show SMILES C[C@H](N)C(=O)NN(Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C40H52N10O6/c1-25(42)36(52)49-50(24-28-15-7-4-8-16-28)40(56)45-26(2)37(53)47-34(22-29-23-44-31-18-10-9-17-30(29)31)39(55)48-33(21-27-13-5-3-6-14-27)38(54)46-32(35(43)51)19-11-12-20-41/h3-10,13-18,23,25-26,32-34,44H,11-12,19-22,24,41-42H2,1-2H3,(H2,43,51)(H,45,56)(H,46,54)(H,47,53)(H,48,55)(H,49,52)/t25-,26-,32-,33+,34-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Displacement of photoactivatable [125I]-Tyr-Bpa-Ala-Hexarelin from CD36 in Sprague-Dawley rat cardiac membranes incubated for 60 mins by densitometry				J Med Chem 55: 6502-11 (2012) Article DOI: 10.1021/jm300557t BindingDB Entry DOI: 10.7270/Q22J6D00
					More data for this Ligand-Target Pair
Platelet glycoprotein 4 (Rattus norvegicus)	BDBM50394993 (CHEMBL2163485 | US9708370, CP-1A(iv)) Show SMILES C[C@H](N)C(=O)NN(Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C40H52N10O6/c1-25(42)36(52)49-50(24-28-15-7-4-8-16-28)40(56)45-26(2)37(53)47-34(22-29-23-44-31-18-10-9-17-30(29)31)39(55)48-33(21-27-13-5-3-6-14-27)38(54)46-32(35(43)51)19-11-12-20-41/h3-10,13-18,23,25-26,32-34,44H,11-12,19-22,24,41-42H2,1-2H3,(H2,43,51)(H,45,56)(H,46,54)(H,47,53)(H,48,55)(H,49,52)/t25-,26-,32-,33+,34-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.02E+3	n/a	n/a	n/a	n/a	7.3	n/a
VALORISATION-RECHERCHE, LIMITED PARTNERSHIP; VALORISATION HSJ, LIMITED PARTNERSHIP US Patent					Assay Description Competition experiments were performed by incubating 50 μg of LLC-PK1 membranes expressing human GHS-R1a with 15 fmol of 125I-Ghrelin and increa...				US Patent US9708370 (2017) BindingDB Entry DOI: 10.7270/Q2XP76ZK
					More data for this Ligand-Target Pair
Estrogen receptor alpha D538G (Homo sapiens (Human))	BDBM50394993 (CHEMBL2163485 | US9708370, CP-1A(iv)) Show SMILES C[C@H](N)C(=O)NN(Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C40H52N10O6/c1-25(42)36(52)49-50(24-28-15-7-4-8-16-28)40(56)45-26(2)37(53)47-34(22-29-23-44-31-18-10-9-17-30(29)31)39(55)48-33(21-27-13-5-3-6-14-27)38(54)46-32(35(43)51)19-11-12-20-41/h3-10,13-18,23,25-26,32-34,44H,11-12,19-22,24,41-42H2,1-2H3,(H2,43,51)(H,45,56)(H,46,54)(H,47,53)(H,48,55)(H,49,52)/t25-,26-,32-,33+,34-/m0/s1	PDB GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
VALORISATION-RECHERCHE, LIMITED PARTNERSHIP; VALORISATION HSJ, LIMITED PARTNERSHIP US Patent					Assay Description GHS-R1a radioreceptor assay using LLCPK-1 membranes overexpressing GSH-R1a and radioiodinated (1-28) rat ghrelin as tracer.				US Patent US9708370 (2017) BindingDB Entry DOI: 10.7270/Q2XP76ZK
					More data for this Ligand-Target Pair
Ghrelin receptor (Homo sapiens (Human))	BDBM50394993 (CHEMBL2163485 | US9708370, CP-1A(iv)) Show SMILES C[C@H](N)C(=O)NN(Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C40H52N10O6/c1-25(42)36(52)49-50(24-28-15-7-4-8-16-28)40(56)45-26(2)37(53)47-34(22-29-23-44-31-18-10-9-17-30(29)31)39(55)48-33(21-27-13-5-3-6-14-27)38(54)46-32(35(43)51)19-11-12-20-41/h3-10,13-18,23,25-26,32-34,44H,11-12,19-22,24,41-42H2,1-2H3,(H2,43,51)(H,45,56)(H,46,54)(H,47,53)(H,48,55)(H,49,52)/t25-,26-,32-,33+,34-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]ghrelin expressed in in LLC-PK1 cells incubated for 1 hr by gamma counting method				J Med Chem 55: 6502-11 (2012) Article DOI: 10.1021/jm300557t BindingDB Entry DOI: 10.7270/Q22J6D00
					More data for this Ligand-Target Pair