BDBM50395002 CHEMBL2163477::US9708370, DBG-201-A

SMILES: CC(C)CN(NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key: InChIKey=ORVDMPNOTALZCE-OSKJDNRQSA-N

Data: 3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50395002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet glycoprotein 4 (Rattus norvegicus)	BDBM50395002 (CHEMBL2163477 | US9708370, DBG-201-A) Show SMILES CC(C)CN(NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C48H61N13O6/c1-29(2)27-61(60-47(66)42(22-32-25-54-38-17-9-7-15-35(32)38)57-44(63)36(50)23-33-26-52-28-55-33)48(67)59-41(21-31-24-53-37-16-8-6-14-34(31)37)46(65)58-40(20-30-12-4-3-5-13-30)45(64)56-39(43(51)62)18-10-11-19-49/h3-9,12-17,24-26,28-29,36,39-42,53-54H,10-11,18-23,27,49-50H2,1-2H3,(H2,51,62)(H,52,55)(H,56,64)(H,57,63)(H,58,65)(H,59,67)(H,60,66)/t36-,39-,40+,41-,42+/m0/s1	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Displacement of photoactivatable [125I]-Tyr-Bpa-Ala-Hexarelin from CD36 in Sprague-Dawley rat cardiac membranes incubated for 60 mins by densitometry				J Med Chem 55: 6502-11 (2012) Article DOI: 10.1021/jm300557t BindingDB Entry DOI: 10.7270/Q22J6D00
					More data for this Ligand-Target Pair
Estrogen receptor alpha D538G (Homo sapiens (Human))	BDBM50395002 (CHEMBL2163477 | US9708370, DBG-201-A) Show SMILES CC(C)CN(NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C48H61N13O6/c1-29(2)27-61(60-47(66)42(22-32-25-54-38-17-9-7-15-35(32)38)57-44(63)36(50)23-33-26-52-28-55-33)48(67)59-41(21-31-24-53-37-16-8-6-14-34(31)37)46(65)58-40(20-30-12-4-3-5-13-30)45(64)56-39(43(51)62)18-10-11-19-49/h3-9,12-17,24-26,28-29,36,39-42,53-54H,10-11,18-23,27,49-50H2,1-2H3,(H2,51,62)(H,52,55)(H,56,64)(H,57,63)(H,58,65)(H,59,67)(H,60,66)/t36-,39-,40+,41-,42+/m0/s1	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
VALORISATION-RECHERCHE, LIMITED PARTNERSHIP; VALORISATION HSJ, LIMITED PARTNERSHIP US Patent					Assay Description GHS-R1a radioreceptor assay using LLCPK-1 membranes overexpressing GSH-R1a and radioiodinated (1-28) rat ghrelin as tracer.				US Patent US9708370 (2017) BindingDB Entry DOI: 10.7270/Q2XP76ZK
					More data for this Ligand-Target Pair
Platelet glycoprotein 4 (Rattus norvegicus)	BDBM50395002 (CHEMBL2163477 | US9708370, DBG-201-A) Show SMILES CC(C)CN(NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C48H61N13O6/c1-29(2)27-61(60-47(66)42(22-32-25-54-38-17-9-7-15-35(32)38)57-44(63)36(50)23-33-26-52-28-55-33)48(67)59-41(21-31-24-53-37-16-8-6-14-34(31)37)46(65)58-40(20-30-12-4-3-5-13-30)45(64)56-39(43(51)62)18-10-11-19-49/h3-9,12-17,24-26,28-29,36,39-42,53-54H,10-11,18-23,27,49-50H2,1-2H3,(H2,51,62)(H,52,55)(H,56,64)(H,57,63)(H,58,65)(H,59,67)(H,60,66)/t36-,39-,40+,41-,42+/m0/s1	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.89E+3	n/a	n/a	n/a	n/a	7.3	n/a
VALORISATION-RECHERCHE, LIMITED PARTNERSHIP; VALORISATION HSJ, LIMITED PARTNERSHIP US Patent					Assay Description Competition experiments were performed by incubating 50 μg of LLC-PK1 membranes expressing human GHS-R1a with 15 fmol of 125I-Ghrelin and increa...				US Patent US9708370 (2017) BindingDB Entry DOI: 10.7270/Q2XP76ZK
					More data for this Ligand-Target Pair
Ghrelin receptor (Homo sapiens (Human))	BDBM50395002 (CHEMBL2163477 | US9708370, DBG-201-A) Show SMILES CC(C)CN(NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C48H61N13O6/c1-29(2)27-61(60-47(66)42(22-32-25-54-38-17-9-7-15-35(32)38)57-44(63)36(50)23-33-26-52-28-55-33)48(67)59-41(21-31-24-53-37-16-8-6-14-34(31)37)46(65)58-40(20-30-12-4-3-5-13-30)45(64)56-39(43(51)62)18-10-11-19-49/h3-9,12-17,24-26,28-29,36,39-42,53-54H,10-11,18-23,27,49-50H2,1-2H3,(H2,51,62)(H,52,55)(H,56,64)(H,57,63)(H,58,65)(H,59,67)(H,60,66)/t36-,39-,40+,41-,42+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]ghrelin expressed in in LLC-PK1 cells incubated for 1 hr by gamma counting method				J Med Chem 55: 6502-11 (2012) Article DOI: 10.1021/jm300557t BindingDB Entry DOI: 10.7270/Q22J6D00
					More data for this Ligand-Target Pair