BDBM50395024 CHEMBL2163444::US9708370, CP-2A(v)

SMILES: C[C@H](N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NNC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key: InChIKey=VLVLTJYWRZVAJZ-PDKHXXOHSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50395024   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50395024 (CHEMBL2163444 | US9708370, CP-2A(v)) Show SMILES C[C@H](N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NNC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C41H51N11O6/c1-24(43)37(54)48-35(21-27-23-46-31-16-8-6-14-29(27)31)40(57)51-52-41(58)50-34(20-26-22-45-30-15-7-5-13-28(26)30)39(56)49-33(19-25-11-3-2-4-12-25)38(55)47-32(36(44)53)17-9-10-18-42/h2-8,11-16,22-24,32-35,45-46H,9-10,17-21,42-43H2,1H3,(H2,44,53)(H,47,55)(H,48,54)(H,49,56)(H,51,57)(H2,50,52,58)/t24-,32-,33+,34-,35+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	568	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]ghrelin expressed in in LLC-PK1 cells incubated for 1 hr by gamma counting method				J Med Chem 55: 6502-11 (2012) Article DOI: 10.1021/jm300557t BindingDB Entry DOI: 10.7270/Q22J6D00
					More data for this Ligand-Target Pair
Platelet glycoprotein 4 (Rattus norvegicus)	BDBM50395024 (CHEMBL2163444 | US9708370, CP-2A(v)) Show SMILES C[C@H](N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NNC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C41H51N11O6/c1-24(43)37(54)48-35(21-27-23-46-31-16-8-6-14-29(27)31)40(57)51-52-41(58)50-34(20-26-22-45-30-15-7-5-13-28(26)30)39(56)49-33(19-25-11-3-2-4-12-25)38(55)47-32(36(44)53)17-9-10-18-42/h2-8,11-16,22-24,32-35,45-46H,9-10,17-21,42-43H2,1H3,(H2,44,53)(H,47,55)(H,48,54)(H,49,56)(H,51,57)(H2,50,52,58)/t24-,32-,33+,34-,35+/m0/s1	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.76E+3	n/a	n/a	n/a	n/a	7.3	n/a
VALORISATION-RECHERCHE, LIMITED PARTNERSHIP; VALORISATION HSJ, LIMITED PARTNERSHIP US Patent					Assay Description Competition experiments were performed by incubating 50 μg of LLC-PK1 membranes expressing human GHS-R1a with 15 fmol of 125I-Ghrelin and increa...				US Patent US9708370 (2017) BindingDB Entry DOI: 10.7270/Q2XP76ZK
					More data for this Ligand-Target Pair
Estrogen receptor [D538G] (Homo sapiens (Human))	BDBM50395024 (CHEMBL2163444 | US9708370, CP-2A(v)) Show SMILES C[C@H](N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NNC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C41H51N11O6/c1-24(43)37(54)48-35(21-27-23-46-31-16-8-6-14-29(27)31)40(57)51-52-41(58)50-34(20-26-22-45-30-15-7-5-13-28(26)30)39(56)49-33(19-25-11-3-2-4-12-25)38(55)47-32(36(44)53)17-9-10-18-42/h2-8,11-16,22-24,32-35,45-46H,9-10,17-21,42-43H2,1H3,(H2,44,53)(H,47,55)(H,48,54)(H,49,56)(H,51,57)(H2,50,52,58)/t24-,32-,33+,34-,35+/m0/s1	PDB GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	568	n/a	n/a	n/a	n/a	n/a	n/a
VALORISATION-RECHERCHE, LIMITED PARTNERSHIP; VALORISATION HSJ, LIMITED PARTNERSHIP US Patent					Assay Description GHS-R1a radioreceptor assay using LLCPK-1 membranes overexpressing GSH-R1a and radioiodinated (1-28) rat ghrelin as tracer.				US Patent US9708370 (2017) BindingDB Entry DOI: 10.7270/Q2XP76ZK
					More data for this Ligand-Target Pair
Platelet glycoprotein 4 (Rattus norvegicus)	BDBM50395024 (CHEMBL2163444 | US9708370, CP-2A(v)) Show SMILES C[C@H](N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NNC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C41H51N11O6/c1-24(43)37(54)48-35(21-27-23-46-31-16-8-6-14-29(27)31)40(57)51-52-41(58)50-34(20-26-22-45-30-15-7-5-13-28(26)30)39(56)49-33(19-25-11-3-2-4-12-25)38(55)47-32(36(44)53)17-9-10-18-42/h2-8,11-16,22-24,32-35,45-46H,9-10,17-21,42-43H2,1H3,(H2,44,53)(H,47,55)(H,48,54)(H,49,56)(H,51,57)(H2,50,52,58)/t24-,32-,33+,34-,35+/m0/s1	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Displacement of photoactivatable [125I]-Tyr-Bpa-Ala-Hexarelin from CD36 in Sprague-Dawley rat cardiac membranes incubated for 60 mins by densitometry				J Med Chem 55: 6502-11 (2012) Article DOI: 10.1021/jm300557t BindingDB Entry DOI: 10.7270/Q22J6D00
					More data for this Ligand-Target Pair