BDBM50395151 CHEMBL2163948

SMILES: CCC1COc2c(OC)ccc3c2n1cc(C(=O)NC12CC4CC(CC(C4)C1)C2)c3=O

InChI Key: InChIKey=GZYUOGNPBFAMCO-UHFFFAOYSA-N

Data: 4 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50395151   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50395151 (CHEMBL2163948) Show SMILES CCC1COc2c(OC)ccc3c2n1cc(C(=O)NC12CC4CC(CC(C4)C1)C2)c3=O |THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25| Show InChI InChI=1S/C25H30N2O4/c1-3-17-13-31-23-20(30-2)5-4-18-21(23)27(17)12-19(22(18)28)24(29)26-25-9-14-6-15(10-25)8-16(7-14)11-25/h4-5,12,14-17H,3,6-11,13H2,1-2H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in CHO cell membranes incubated for 60 mins by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rattus norvegicus (Rat))	BDBM50395151 (CHEMBL2163948) Show SMILES CCC1COc2c(OC)ccc3c2n1cc(C(=O)NC12CC4CC(CC(C4)C1)C2)c3=O |THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25| Show InChI InChI=1S/C25H30N2O4/c1-3-17-13-31-23-20(30-2)5-4-18-21(23)27(17)12-19(22(18)28)24(29)26-25-9-14-6-15(10-25)8-16(7-14)11-25/h4-5,12,14-17H,3,6-11,13H2,1-2H3,(H,26,29)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB2 receptor in Sprague-Dawley rat spleen by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50395151 (CHEMBL2163948) Show SMILES CCC1COc2c(OC)ccc3c2n1cc(C(=O)NC12CC4CC(CC(C4)C1)C2)c3=O |THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25| Show InChI InChI=1S/C25H30N2O4/c1-3-17-13-31-23-20(30-2)5-4-18-21(23)27(17)12-19(22(18)28)24(29)26-25-9-14-6-15(10-25)8-16(7-14)11-25/h4-5,12,14-17H,3,6-11,13H2,1-2H3,(H,26,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	521	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cell membranes incubated for 90 mins by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50395151 (CHEMBL2163948) Show SMILES CCC1COc2c(OC)ccc3c2n1cc(C(=O)NC12CC4CC(CC(C4)C1)C2)c3=O |THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25| Show InChI InChI=1S/C25H30N2O4/c1-3-17-13-31-23-20(30-2)5-4-18-21(23)27(17)12-19(22(18)28)24(29)26-25-9-14-6-15(10-25)8-16(7-14)11-25/h4-5,12,14-17H,3,6-11,13H2,1-2H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat brain by scintillation counting				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50395151 (CHEMBL2163948) Show SMILES CCC1COc2c(OC)ccc3c2n1cc(C(=O)NC12CC4CC(CC(C4)C1)C2)c3=O |THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25| Show InChI InChI=1S/C25H30N2O4/c1-3-17-13-31-23-20(30-2)5-4-18-21(23)27(17)12-19(22(18)28)24(29)26-25-9-14-6-15(10-25)8-16(7-14)11-25/h4-5,12,14-17H,3,6-11,13H2,1-2H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-induced cAMP accumulation				J Med Chem 55: 6608-23 (2012) Article DOI: 10.1021/jm300763w BindingDB Entry DOI: 10.7270/Q2WS8VCX
					More data for this Ligand-Target Pair