Found 9 hits for monomerid = 50395206 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50395206
(CHEMBL2164354)Show SMILES O=C(C1CCCCC1)N(CCN1CCC(=CC1)c1ccccc1)c1ccccn1 |c:15| Show InChI InChI=1S/C25H31N3O/c29-25(23-11-5-2-6-12-23)28(24-13-7-8-16-26-24)20-19-27-17-14-22(15-18-27)21-9-3-1-4-10-21/h1,3-4,7-10,13-14,16,23H,2,5-6,11-12,15,17-20H2 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 0.510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Li£ge
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5-HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting |
Bioorg Med Chem Lett 22: 4550-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50395206
(CHEMBL2164354)Show SMILES O=C(C1CCCCC1)N(CCN1CCC(=CC1)c1ccccc1)c1ccccn1 |c:15| Show InChI InChI=1S/C25H31N3O/c29-25(23-11-5-2-6-12-23)28(24-13-7-8-16-26-24)20-19-27-17-14-22(15-18-27)21-9-3-1-4-10-21/h1,3-4,7-10,13-14,16,23H,2,5-6,11-12,15,17-20H2 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 0.690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Li£ge
Curated by ChEMBL
| Assay Description Binding affinity to 5HT1A receptor by radioligand binding assay |
Bioorg Med Chem Lett 22: 4550-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50395206
(CHEMBL2164354)Show SMILES O=C(C1CCCCC1)N(CCN1CCC(=CC1)c1ccccc1)c1ccccn1 |c:15| Show InChI InChI=1S/C25H31N3O/c29-25(23-11-5-2-6-12-23)28(24-13-7-8-16-26-24)20-19-27-17-14-22(15-18-27)21-9-3-1-4-10-21/h1,3-4,7-10,13-14,16,23H,2,5-6,11-12,15,17-20H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Li£ge
Curated by ChEMBL
| Assay Description Binding affinity to adrenergic alpha1A receptor by radioligand binding assay |
Bioorg Med Chem Lett 22: 4550-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50395206
(CHEMBL2164354)Show SMILES O=C(C1CCCCC1)N(CCN1CCC(=CC1)c1ccccc1)c1ccccn1 |c:15| Show InChI InChI=1S/C25H31N3O/c29-25(23-11-5-2-6-12-23)28(24-13-7-8-16-26-24)20-19-27-17-14-22(15-18-27)21-9-3-1-4-10-21/h1,3-4,7-10,13-14,16,23H,2,5-6,11-12,15,17-20H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Li£ge
Curated by ChEMBL
| Assay Description Binding affinity to 5HT2A receptor by radioligand binding assay |
Bioorg Med Chem Lett 22: 4550-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50395206
(CHEMBL2164354)Show SMILES O=C(C1CCCCC1)N(CCN1CCC(=CC1)c1ccccc1)c1ccccn1 |c:15| Show InChI InChI=1S/C25H31N3O/c29-25(23-11-5-2-6-12-23)28(24-13-7-8-16-26-24)20-19-27-17-14-22(15-18-27)21-9-3-1-4-10-21/h1,3-4,7-10,13-14,16,23H,2,5-6,11-12,15,17-20H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Li£ge
Curated by ChEMBL
| Assay Description Binding affinity to dopamine D4 receptor by radioligand binding assay |
Bioorg Med Chem Lett 22: 4550-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50395206
(CHEMBL2164354)Show SMILES O=C(C1CCCCC1)N(CCN1CCC(=CC1)c1ccccc1)c1ccccn1 |c:15| Show InChI InChI=1S/C25H31N3O/c29-25(23-11-5-2-6-12-23)28(24-13-7-8-16-26-24)20-19-27-17-14-22(15-18-27)21-9-3-1-4-10-21/h1,3-4,7-10,13-14,16,23H,2,5-6,11-12,15,17-20H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Li£ge
Curated by ChEMBL
| Assay Description Binding affinity to 5HT7 receptor by radioligand binding assay |
Bioorg Med Chem Lett 22: 4550-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50395206
(CHEMBL2164354)Show SMILES O=C(C1CCCCC1)N(CCN1CCC(=CC1)c1ccccc1)c1ccccn1 |c:15| Show InChI InChI=1S/C25H31N3O/c29-25(23-11-5-2-6-12-23)28(24-13-7-8-16-26-24)20-19-27-17-14-22(15-18-27)21-9-3-1-4-10-21/h1,3-4,7-10,13-14,16,23H,2,5-6,11-12,15,17-20H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 105 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Li£ge
Curated by ChEMBL
| Assay Description Binding affinity to 5HT2B receptor by radioligand binding assay |
Bioorg Med Chem Lett 22: 4550-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V |
More data for this Ligand-Target Pair | |
Adrenergic alpha1B
(Homo sapiens (Human)) | BDBM50395206
(CHEMBL2164354)Show SMILES O=C(C1CCCCC1)N(CCN1CCC(=CC1)c1ccccc1)c1ccccn1 |c:15| Show InChI InChI=1S/C25H31N3O/c29-25(23-11-5-2-6-12-23)28(24-13-7-8-16-26-24)20-19-27-17-14-22(15-18-27)21-9-3-1-4-10-21/h1,3-4,7-10,13-14,16,23H,2,5-6,11-12,15,17-20H2 | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 296 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Li£ge
Curated by ChEMBL
| Assay Description Binding affinity to adrenergic alpha1B receptor by radioligand binding assay |
Bioorg Med Chem Lett 22: 4550-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50395206
(CHEMBL2164354)Show SMILES O=C(C1CCCCC1)N(CCN1CCC(=CC1)c1ccccc1)c1ccccn1 |c:15| Show InChI InChI=1S/C25H31N3O/c29-25(23-11-5-2-6-12-23)28(24-13-7-8-16-26-24)20-19-27-17-14-22(15-18-27)21-9-3-1-4-10-21/h1,3-4,7-10,13-14,16,23H,2,5-6,11-12,15,17-20H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 385 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Li£ge
Curated by ChEMBL
| Assay Description Displacement of [3H]-YM-09151-2 from human cloned D4 receptor expressed in Sf9 cells after 60 mins by liquid scintillation counting |
Bioorg Med Chem Lett 22: 4550-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V |
More data for this Ligand-Target Pair | |