BindingDB PrimarySearch

BDBM50395207 CHEMBL2164350

SMILES: O=C(C1CCCCC1)N(CCN1CCN(CC1)c1ccccc1)c1ccccn1

InChI Key: InChIKey=QJFWBEXGRNKZIY-UHFFFAOYSA-N

Data: 9 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50395207
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50395207 (CHEMBL2164350) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5-HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 22: 4550-4 (2012) Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V
University of Li£ge Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50395207 (CHEMBL2164350) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor by radioligand binding assay				Bioorg Med Chem Lett 22: 4550-4 (2012) Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V
University of Li£ge Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50395207 (CHEMBL2164350) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor by radioligand binding assay				Bioorg Med Chem Lett 22: 4550-4 (2012) Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V
University of Li£ge Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50395207 (CHEMBL2164350) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	198	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Binding affinity to 5HT7 receptor by radioligand binding assay				Bioorg Med Chem Lett 22: 4550-4 (2012) Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V
University of Li£ge Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50395207 (CHEMBL2164350) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	246	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Binding affinity to dopamine D4 receptor by radioligand binding assay				Bioorg Med Chem Lett 22: 4550-4 (2012) Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V
University of Li£ge Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50395207 (CHEMBL2164350) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	327	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Binding affinity to 5HT2B receptor by radioligand binding assay				Bioorg Med Chem Lett 22: 4550-4 (2012) Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V
University of Li£ge Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50395207 (CHEMBL2164350) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	584	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Binding affinity to adrenergic alpha1A receptor by radioligand binding assay				Bioorg Med Chem Lett 22: 4550-4 (2012) Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V
University of Li£ge Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50395207 (CHEMBL2164350) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	946	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 from human cloned D4 receptor expressed in Sf9 cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 22: 4550-4 (2012) Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V
University of Li£ge Curated by ChEMBL					More data for this Ligand-Target Pair
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50395207 (CHEMBL2164350) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Binding affinity to adrenergic alpha1B receptor by radioligand binding assay				Bioorg Med Chem Lett 22: 4550-4 (2012) Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V
University of Li£ge Curated by ChEMBL					More data for this Ligand-Target Pair