BDBM50395216 CHEMBL2164347
SMILES: COc1ccccc1N1CCN(CCN(C(=O)c2ccc3ccccc3c2)c2ccccn2)CC1
InChI Key: InChIKey=ZDHWQNDDDURZGC-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50395216 (CHEMBL2164347) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.61 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Li£ge Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5-HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 22: 4550-4 (2012) Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50395216 (CHEMBL2164347) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 184 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Li£ge Curated by ChEMBL | Assay Description Displacement of [3H]-YM-09151-2 from human cloned D4 receptor expressed in Sf9 cells after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 22: 4550-4 (2012) Article DOI: 10.1016/j.bmcl.2012.05.119 BindingDB Entry DOI: 10.7270/Q2HH6M6V | |||||||||||
More data for this Ligand-Target Pair |