BDBM50395382 CHEMBL2164724
SMILES: CC(CCSCC[C@H](N)C(O)=O)CCC(N)C(O)=O
InChI Key: InChIKey=DIYYUYXXASDSMO-RTBKNWGFSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S-methylmethionine--homocysteine S-methyltransferase BHMT2 (Homo sapiens (Human)) | BDBM50395382 (CHEMBL2164724) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 77 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Sciences of the Czech Republic Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human BHMT2 expressed in Escherichia coli BL31(DE3) by Dixon plot method in presence of D,L-homocysteine | J Med Chem 55: 6822-31 (2012) Article DOI: 10.1021/jm300571h BindingDB Entry DOI: 10.7270/Q2BV7HSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methylmethionine--homocysteine S-methyltransferase BHMT2 (Homo sapiens (Human)) | BDBM50395382 (CHEMBL2164724) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Sciences of the Czech Republic Curated by ChEMBL | Assay Description Inhibition of recombinant human BHMT2 expressed in Escherichia coli BL31(DE3) | J Med Chem 55: 6822-31 (2012) Article DOI: 10.1021/jm300571h BindingDB Entry DOI: 10.7270/Q2BV7HSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Betaine--homocysteine S-methyltransferase 1 (Homo sapiens (Human)) | BDBM50395382 (CHEMBL2164724) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Sciences of the Czech Republic Curated by ChEMBL | Assay Description Inhibition of recombinant human BHMT expressed in Escherichia coli BL31(DE3) | J Med Chem 55: 6822-31 (2012) Article DOI: 10.1021/jm300571h BindingDB Entry DOI: 10.7270/Q2BV7HSH | |||||||||||
More data for this Ligand-Target Pair |