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BDBM50395466 CHEMBL2163685

SMILES: CN(Cc1ccccc1)c1ccccc1NC(=O)Cc1cccc(Cl)c1

InChI Key: InChIKey=MDCGAKUGBRILGP-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395466   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
KCNQ (Kv7) potassium channel


(Homo sapiens (Human))
BDBM50395466
PNG
(CHEMBL2163685)
Show SMILES CN(Cc1ccccc1)c1ccccc1NC(=O)Cc1cccc(Cl)c1
Show InChI InChI=1S/C22H21ClN2O/c1-25(16-17-8-3-2-4-9-17)21-13-6-5-12-20(21)24-22(26)15-18-10-7-11-19(23)14-18/h2-14H,15-16H2,1H3,(H,24,26)
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KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Agonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assay


J Med Chem 55: 6975-9 (2012)


Article DOI: 10.1021/jm300700v
BindingDB Entry DOI: 10.7270/Q2KD2017
More data for this
Ligand-Target Pair