BDBM50395466 CHEMBL2163685

SMILES: CN(Cc1ccccc1)c1ccccc1NC(=O)Cc1cccc(Cl)c1

InChI Key: InChIKey=MDCGAKUGBRILGP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395466   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
KCNQ (Kv7) potassium channel (Homo sapiens (Human))	BDBM50395466 (CHEMBL2163685) Show SMILES CN(Cc1ccccc1)c1ccccc1NC(=O)Cc1cccc(Cl)c1 Show InChI InChI=1S/C22H21ClN2O/c1-25(16-17-8-3-2-4-9-17)21-13-6-5-12-20(21)24-22(26)15-18-10-7-11-19(23)14-18/h2-14H,15-16H2,1H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Agonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assay				J Med Chem 55: 6975-9 (2012) Article DOI: 10.1021/jm300700v BindingDB Entry DOI: 10.7270/Q2KD2017
					More data for this Ligand-Target Pair