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BDBM50395467 CHEMBL2163678

SMILES: CN(C)c1ccccc1NC(=O)Cc1cccc(Cl)c1

InChI Key: InChIKey=ZMGXDQCEPADWPM-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395467   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
KCNQ (Kv7) potassium channel


(Homo sapiens (Human))
BDBM50395467
PNG
(CHEMBL2163678)
Show SMILES CN(C)c1ccccc1NC(=O)Cc1cccc(Cl)c1
Show InChI InChI=1S/C16H17ClN2O/c1-19(2)15-9-4-3-8-14(15)18-16(20)11-12-6-5-7-13(17)10-12/h3-10H,11H2,1-2H3,(H,18,20)
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.74E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Agonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assay


J Med Chem 55: 6975-9 (2012)


Article DOI: 10.1021/jm300700v
BindingDB Entry DOI: 10.7270/Q2KD2017
More data for this
Ligand-Target Pair