BDBM50395473 CHEMBL2163666

SMILES: Clc1cccc(CC(=O)Nc2cccc(c2)N2CCCC2)c1

InChI Key: InChIKey=BHFMDROWZJGHES-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
KCNQ (Kv7) potassium channel (Homo sapiens (Human))	BDBM50395473 (CHEMBL2163666) Show SMILES Clc1cccc(CC(=O)Nc2cccc(c2)N2CCCC2)c1 Show InChI InChI=1S/C18H19ClN2O/c19-15-6-3-5-14(11-15)12-18(22)20-16-7-4-8-17(13-16)21-9-1-2-10-21/h3-8,11,13H,1-2,9-10,12H2,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Agonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assay				J Med Chem 55: 6975-9 (2012) Article DOI: 10.1021/jm300700v BindingDB Entry DOI: 10.7270/Q2KD2017
					More data for this Ligand-Target Pair